In this episode of Channels, the Nextflow podcast, host Geraldine Van der Auwera from Seqera and her colleague Ben Sherman dive into the differences and similarities between Nextflow and the Workflow Description Language (WDL). They discuss the origins and development of WDL at the Broad Institute, the challenges of working with different workflow languages, and how Nextflow’s channel-based data flow model compares to WDL’s approach. The conversation covers key features, type systems, and runtime specifications, highlighting the strengths and limitations of both languages. Ben hints at upcoming improvements and enhancements for Nextflow, aimed at making the language more robust and user-friendly. The episode offers valuable insights for bioinformaticians and developers navigating the complexities of workflow management.
In episode 45 of the Channels podcast, Sasha Dagayev from Seqera (formerly tinybio) shares his journey from working in tech and consumer spaces to entering bioinformatics during the pandemic. Sasha discusses the challenges and innovations behind tinybio, including the evolution towards integrating Generative AI (ChatGPT) to simplify bioinformatics tasks. <!-- end-archive-description --> We discuss:
In episode 44 of the Channels podcast, Phil Ewels Phil talks with Alex Pelzer, a key figure in the Nextflow and nf-core communities, about regulatory aspects of bioinformatics and Nextflow pipelines. We talk about Alex’s background, his experience in academia(QBiC) and industry (Boehringer Ingelheim), and the importance of regulatory compliance in bioinformatics workflows. We discuss how documentation, software testing, and standardization all plays a part in ensuring pipeline reliability for clinical trials. Finally, we highlight the newly formed nf-core Regulatory Special Interest Group, aiming to collaborate on best practices and standards for bioinformatics pipelines.
A small but intrepid team of Seqerans recently attended the ISMB 2024 conference in Montreal, a great mix of computational biology and bioinformatics with a largely academic / research-focused audience. Join Geraldine Van der Auwera, Rob Syme and Florian Wuennemann for a lively discussion about the scientific themes of the conference, their experience running a booth, meeting with the ISMB and BOSC community, and resources for job seekers.
Join us to hear Phil Ewels chat with Maxime Garcia and Franziska Bonath about how nf-core started at the National Genomics Infrastructure (NGI) at SciLifeLab in Sweden. We chat about how the nf-core/sarek pipeline grew alongside and eventually joined nf-core, as well as the early days of nf-core bytesize talks and outreach organisation.
Join us in this episode of the Channels podcast for a closer look at the Nextflow Ambassadors, a worldwide initiative designed to foster collaboration, knowledge sharing, and community growth. It is intended to recognize and support the efforts of our community leaders and marks another step forward in our mission to advance scientific research and empower researchers. Marcel Ribeiro-Dantas and Geraldine Van der Auwera discuss the origins of the program, recent highlights and next steps, including the open call for new Ambassadors, which will close June 14.
In a special edition of the Channels Podcast, Geraldine Van der Auwera interviews four members of the Nextflow community attending the 2023 nf-core hackathon: Raquel Manzano, Edmund Miller, Rieke Hanssen and Francesco Lescai. Recorded in-person at the Nextflow Summit Barcelona, we hear a bit about what they have been working on, how they came to use Nextflow and what motivated them to join the nf-core hackathon.
In this News and Views episode, Phil Ewels, Chris Hakkaart and Marcel Ribeiro-Dantas play with interactive debuggers in IntelliJ to try to understand what’s happening in their pipeline. We also give a first look at plans for a brand new “Nextflow Ambassador” program that we’ll be launching soon, as well as a revamped training course that was rescued from the precipice.
Rob Lalonde of Seqera interviews Robert Petit, a senior bioinformatics scientist at Wyoming Public Health Laboratory. In this interview, Rob and Rob discuss public health challenges unique to Wyoming, genomic surveillance, the Bactopia pipeline, and the latest fashion trends among leading bioinformaticians in the state.
In this Podcast, Rob Lalonde of Seqera speaks with Cedric Notredame, head of the Notredame Lab at the Centre for Genomic Regulation in Barcelona, Spain. In this far-ranging discussion, Rob and Cedric talk about cloud, pipelines, and trace the evolution of Nextflow from its early days as a research project to its current role in the global COVID effort.
In this podcast, Rob Lalonde of Seqera speaks with Lorena Pantano, head of Computational Biology at NextRNA, a firm leading the next revolution in RNA-directed therapeutics located in Cambridge, Massachusetts. In this fascinating discussion, Rob and Lorena talk bioinformatics, life in a startup, and women in technology.